Hideaki Mizuno

Publications
ERK Signal Suppression and Sensitivity to CH5183284/Debio 1347, a Selective FGFR Inhibitor. Nakanishi Y, Mizuno H, Sase H, Fujii T, Sakata K, Akiyama N, Aoki Y, Aoki M, Ishii N. Mol Cancer Ther. 2015, 14:2831-9.
The AURKA/TPX2 axis drives colon tumorigenesis cooperatively with MYC. Takahashi Y, Sheridan P, Niida A, Sawada G, Uchi R, Mizuno H, Kurashige J, Sugimachi K, Sasaki S, Shimada Y, Hase K, Kusunoki M, Kudo S, Watanabe M, Yamada K, Sugihara K, Yamamoto H, Suzuki A, Doki Y, Miyano S, Mori M, Mimori K. Ann Oncol. 2015, 26:935-42.
The PFA-AMeX method achieves a good balance between the morphology of tissues and the quality of RNA content in DNA microarray analysis with laser-capture microdissection samples.Watanabe T, Kato A, Terashima H, Matsubara K, Chen YJ, Adachi K, Mizuno H, Suzuki M. J Toxicol Pathol. 2015, 28:43-9.
Topological analysis of gene expression arrays identifies high risk molecular subtypes in breast cancer. Arsuaga J, Baas N, DeWoskin D, Mizuno H, Pankov A, Park C. Applicable Algebra in Engineering, Communication and Computing. 2012, 23:3-15.
Mutant p53 Disrupts Mammary Tissue Architecture via the Mevalonate Pathway. Freed-Pastor WA, Mizuno H, Zhao X, Langerød A, Moon SH, Rodriguez-Barrueco R, Barsotti A, Chicas A, Li W, Polotskaia A, Bissell MJ, Osborne TF, Tian B, Lowe SW, Silva JM, Børresen-Dale AL, Levine AJ, Bargonetti J, Prives C. Cell. 2012, 148:244-58.
Molecular classification of prostate cancer using curated expression signatures. Markert EK, Mizuno H, Vazquez A, Levine AJ. Proc Natl Acad Sci U S A. 2011, 108:21276-81.
Identification of Genes Up-regulated in ALK-positive and EGFR/KRAS/ALK-negative Lung Adenocarcinomas. Okayama H, Kohno T, Ishii Y, Shimada Y, Shiraishi K, Iwakawa R, Furuta K, Tsuta K, Shibata T, Yamamoto S, Watanabe SI, Sakamoto H, Kumamoto K, Takenoshita S, Gotoh N, Mizuno H, Sarai A, Kawano S, Yamaguchi R, Miyano S, Yokota J. Cancer Res. 2010, 72:100-111.
Inactivation of p53 in breast cancers correlates with stem cell transcriptional signatures. Mizuno H, Spike BT, Wahl GM, Levine AJ. Proc Natl Acad Sci U S A. 2010, 107:22745-50.
Fine-scale detection of population-specific linkage disequilibrium using haplotype entropy in the human genome. Mizuno H, Atwal G, Wang H, Levine AJ, Vazquez A. BMC Genetics 2010, 11:27.
ENIGMA - Japanese abstract
PrognoScan: A new database for meta-analysis of the prognostic value of genes. Mizuno H, Kitada K, Nakai K, Sarai A. BMC Med Genomics. 2009, 2:18.
PrognoScan - Japanese abstract
A signature-based method for indexing cell cycle phase distribution from microarray profiles. Mizuno H, Nakanishi Y, Ishii N, Sarai A, Kitada K. BMC Genomics. 2009, 10:137.
Chip data
Involvement of cyclooxygenase-2 in the tumor site-dependent production of parathyroid hormone-related protein in colon 26 carcinoma. Saito H, Inagaki Y, Tsunenari T, Ura M, Mizuno H, Fujimoto-Ouchi K, Onuma E, Sato K, Ogata E, Yamada-Okabe H. Cancer Sci. 2007, 98:1563-9.
ORI-GENE: A Tool for Gene Classification and Prediction of Function Based on the Evolutionary Tree. Mizuno H, Tanaka Y, Nakai K, Sarai A. Bioinformatics. 2001, 17:167-73.
ORI-GENE - Japanese abstract
The Dictyostelium developmental cDNA project: generation and analysis of expressed sequence tags from the first-finger stage of development. Morio T, Urushihara H, Saito T, Ugawa Y, Mizuno H, Yoshida M, Yoshino R, Mitra BN, Pi M, Sato T, Takemoto K, Yasukawa H, Williams J, Maeda M, Takeuchi I, Ochiai H, Tanaka Y. DNA Res. 1998, 5:335-40.
Dictyostelium cDNA Project
Patent
US2010-0267571 NOVEL METHOD FOR SPECIMEN PREPARATION, WHICH ENSURES PRESERVATION OF TISSUE MORPHOLOGY AND NUCLEIC ACID QUALITY. Takeshi Watanabe, Fang Yanting, Masami Suzuki, Hiromichi Terashima, Hideaki Mizuno
Committee Career
2012 - 2013 Board Member, Japanese Society for Bioinformatics (JSBi)
Miscellaneous
Pre-clinical investigation of predictive biomarkers for drug candidates using a molecularly profiled large cancer cell line panel. Satoshi Aida, Hideaki Mizuno, Hiroshi Sakamoto, Yoshito Nakanishi, Hironori Mutoh, James Cai, Helmut Burtscher, Masahiro Aoki, Yuko Aoki, Nobuya Ishii. Mol Cancer Ther 2013, 12:A41.
GIW06Phylogenetic Analysis of Essential Genes by Using ORI-GENE. Kawano H, Mizuno H, Sarai A. Genome Informatics 2006.
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ORI-GENE: A tool for gene analysis based on evolutionary tree. Mizuno H, Tanaka Y, Sarai A. Forty-sixth Annual Meeting of the Biophysical Society of Japan.
Dicty99ORI-GENE: A tool for gene analysis based on evolutionary tree - Application to cDNA project of Dictyostelium discoideum. Mizuno H, Sarai A, Tanaka Y. Dictyostelium international 1999.
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GIW98ORI-GENE: A Tool for Gene Classification Based on Evolutional Tree. Mizuno H, Tanaka Y, Ugawa Y, Sarai A. Genome Informatics 1998.
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